YOUTH EXPERT™

Global Anti-Aging Cream #1

YOUTH EXPERT™ Global Anti-Aging Cream #1 is a richly formulated, luxurious cream dedicated to prestigious skin therapies targeted on global rejuvenation – real results™. Cream is suitable for daily care for skin of all types of age 30~35+.

[RADIANCE + FIRMING]

YOUTH GENE ACTIVATOR

Extraordinary Source of Youth

Free of paraben, colourants

*KLOTHO gene was discovered in 1997, in mice, to extend the lifespan when overexpressed, while it accelerates aging when its expression is disrupted. The name of this longevity gene comes from the Greek goddess Klotho. In Greek mythology, it was Klotho who controlled the lives and destinies of everyone. The Klotho gene codes for a transmembrane protein, the extra-cellular domain of which is shed and secreted. The secreted Klotho protein inhibits the phosphorylation of the IGF1 receptor which leads to the repression of the insulin / IGF-1 pathway. Therefore, Klotho activity results in an activation of **FOXO. Activation of FOXO will induce anti-aging activity by stimulating detoxification and DNA-repair genes.

***The telomere is a region of non-coding DNA that is located at the ends of chromosomes (X- shaped).

****Glutathione peroxidase (GP) is the general name of an enzyme family with peroxidase activity whose main biological role is to protect the organism from oxidative damage. The biochemical function of glutathione peroxidase is to reduce lipid hydroperoxides to their corresponding alcohols and to reduce free hydrogen peroxide to water.

Basic theory (main issues of skin at this age)

• First signs of improper moisture retention in skin – that leads to:

  • Dehydration and roughness

  • Appearing of mimic wrinkles and fine lines

• Reduced microcirculation – that leads to:

  • Decreased level of oxygen in cells

  • Accumulation of free radicals

  • Dull skin tone

Basic theory (needs of skin at this age)

• Radiant complexion (proper microcirculation)

• Intensive moisturisation (wrinkle prevention)

• Supporting cellular activity and detox

• Firming (cell stimulation)

• Photo-protection against UV and free radicals (FR)

Active ingredients*

Leading components

GEN’X-17-GAA™ Complex: Orange Stem Cells + Baicalin (Telomere Protector) + Apitoxin (Bee Venom) + Crystal Tears™

Complementary components – typical to the age group

Energising & Radiance: Liposomes Q10 + Carnitine + Lecithin

Firmness & Elasticity: CycloPeptide-5 (small molecule, cyclic amino acid derivate)

Hydration: Ectoin (increases moisture content and supports immune system of skin, stabilizes cell membranes and protects skin from DNA damage)

Emollient: Cotton Oil

Photo-protection: HDBM (advanced non-UV-absorbing photo-protector against photo-oxidative stress)

Anti-oxidant: Vitamin E

Leading components

GEN’X-17-GAA™ Complex: Orange Stem Cells + Baicalin (Telomere Protector) + Apitoxin (Bee Venom) + Crystal Tears™

Complementary components – typical to the age group

Energising & Radiance: Liposomes Q10 + Carnitine + Lecithin

Firmness & Elasticity: CycloPeptide-5 (small molecule, cyclic amino acid derivate)

Hydration: Ectoin (increases moisture content and supports immune system of skin, stabilizes cell membranes and protects skin from DNA damage)

Emollient: Cotton Oil

Photo-protection: HDBM (advanced non-UV-absorbing photo-protector against photo-oxidative stress)

Anti-oxidant: Vitamin E

Safety

Free of parabens and colourants.

Innovations

• GEN’X-17-GAA™ – a stunning technology Global-Anti-Age (GAA™) that awakes youth genes of skin involved in cellular activity, thus - to stimulate:

  • Synthesis of cellular RNA = by this way cells are more active and their vitality becomes similar to fibroblasts -17 years younger!

  • DNA repair and cellular detoxification

  • Synthesis of fibrillin (a large glycoprotein (~350 kDa), rich in cysteine, which is a main component of microfibrils - its expression is reduced during aging).

• Cyclopeptide-5 –the outstanding and the newest generation of peptides designed to act in the skin with the ultimate in precision. It is the new dimension in effective anti-aging. It contains unique sequence of amino-acids (arginine, glycine, aspartate) as the best configuration to mimic natural processes at the chosen biological target site – the integrins (cell surface receptors).

• HDBM – advanced non-UV-absorbing photo-protector and extremely powerful, innovative anti-oxidant. It prevents premature skin aging efficiently and continuously around-the-clock, i.e. day & night. Protects skin lipids (ideal sebum oxidation control agent). Provides long lasting efficacy and remarkable anti-radical protection.

Directions for use

• Age group: women aged 30~35+

• Dull skin with photo-aging symptoms and first wrinkles

• Global age-preserving therapies on all levels of skin

• All round anti-aging treatment to extend cell lifetime

• Photo-protection against UV and free radicals (FR)

• Daily skin care for skin of all types (night and/or day application)

Treatments types

• Luxurious therapies targeted on global combat against aging

• Age-preserving therapies for skin aged 30~35+

• Treatments targeted on visible effects – improvements of skin texture from first application!

Efficacy of active ingredients*

Benefits provided by leading components include:

• Re-activation of two youth proteins: KLOTHO* and FOXO**

• Re-activation of cellular detoxification and the repair of RNA&DNA damages

• Extension of  the length of telomeres’*** which are responsible for lifespan of cells

• Protection of cells against high levels of free radicals and oxidative stress in the way of the expression of Cit-SAP - a protein with considerable homology to glutathione peroxidase**** (GP)

• Re-activation of cellular activity (synthesis of collagen, elastin and fibrillin)

• Increased microcirculation, thus accelerates skin oxygenation

Benefits provided by ingredients typical to this age group include:

• Increased production of ATP - the key molecule of cell energy

• Improved skin hydration, elasticity and firmness

• Reduced appearance of first wrinkles

• Restored radiant and youthful appearance of skin

Application area

Face, neck, décolletage, other (if desired).

INCI

Aqua, Isopropyl Myristate, Cetearyl Ethylhexanoate, Cyclopentasiloxane, Ethylhexyl Palmitate, Caprylic/Capric Triglyceride, Glycerin, Butylene Glycol, Cetyl Alcohol, Methyl Glucose Sesquistearate, Bis-PEG/PPG-20/5 PEG/PPG-20/5 Dimethicone, Propanediol, Methoxy PEG/PPG-25/4 Dimethicone, Glyceryl Stearate, Gossypium Herbaceum (Cotton) Seed Oil, Citrus Aurantium Dulcis (Orange) Callus Culture Extract, Bis-Ethylhexyl Hydroxydimethoxy Benzylmalonate, Ectoin, Lecithin, Pistacia Lentiscus (Mastic) Gum, Carnitine, Baicalin, Myristyl Myristate, Glyceryl Polyacrylate, Bee Venom, Ubiquinone, Cyclotetrapeptide-24 Aminocyclohexane Carboxylate, Carbomer, Xanthan Gum, Ethylhexylglycerin, Gluconolactone, PVM/MA Copolymer, Sodium Citrate, Calcium Gluconate, Tocopherol, Biotin, Parfum, Sodium Hydroxide, PEG-8, Ascorbyl Palmitate, Ascorbic Acid, Sodium Benzoate, Citric Acid, Potassium Sorbate, PPG-5-Ceteth-20, Trisodium EDTA, Pentaerythrityl Tetra-di-tbutyl Hydroxyhydrocinnamate, Phenoxyethanol, Alcohol, Disodium EDTA.

Cautions

For external use only. Keep out of the reach of children.

Contraindications: hypersensitivity to any component of the formulation.